Article last updated: October 15, 2024
Ursodiol, also known by its chemical name Cholan-24-oic acid, 3,7-dihydroxy-, 3-α, 5-β, 7-β, is a bile acid that is naturally found in the human body. It is also known by other names such as ursodeoxycholic acid (UDCA). Ursodiol is primarily sourced from bile, a digestive fluid produced by the liver. In the context of cosmetics, this ingredient is valued for its skin conditioning and skin protecting properties.
The history of Ursodiol’s use in cosmetics is relatively recent compared to its long-standing medical applications. Initially, Ursodiol was used in the medical field to treat gallstones and certain liver diseases. Its beneficial properties for the skin were discovered later, leading to its incorporation into various skincare products. The transition from medical to cosmetic use was driven by its ability to improve skin hydration, reduce inflammation, and protect the skin barrier.
Ursodiol is typically synthesized through a chemical process that involves the oxidation and reduction of cholic acid, another bile acid. This synthetic production ensures a consistent and pure form of Ursodiol, making it suitable for use in cosmetic formulations. The process involves several steps of purification to remove any impurities, resulting in a high-quality ingredient that can be safely used in skincare products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Ursodiol:
Ursodiol is known for its skin conditioning properties. This means it helps to keep the skin in good condition by improving its appearance and texture. When included in cosmetic formulations, Ursodiol can help to soften and smooth the skin, making it feel more supple and hydrated. This is particularly beneficial for those with dry or rough skin, as it can provide a more even and healthy-looking complexion.
Another key benefit of Ursodiol is its ability to protect the skin. This function involves shielding the skin from environmental stressors and potential irritants. By forming a protective barrier, Ursodiol helps to prevent damage from factors such as pollution, harsh weather, and other external aggressors. This protective quality can be especially useful for individuals with sensitive skin or those who are frequently exposed to harsh environmental conditions.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Ursodiol is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Ursodiol during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Ursodiol are relatively uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
Ursodiol has a comedogenic rating of 1, which means it is unlikely to clog pores. This makes it a suitable option for individuals who are prone to acne, blemishes, or breakouts.
