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Thiomorpholinone: An In-Depth Look at Its Role in Cosmetics

Article last updated: June 14, 2024

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Ever wondered what makes your favorite skincare products so effective? Dive into the fascinating world of Thiomorpholinone and discover its transformative role in cosmetics, from its creation to its incredible benefits and potential side effects.

What Is Thiomorpholinone?

Thiomorpholinone, also known as Thiomorpholin-3-one, is a synthetic compound primarily used in the cosmetic industry for its antioxidant and skin conditioning properties. This ingredient is a sulfur-containing heterocycle, which means it has a ring structure that includes sulfur atoms. Its unique chemical composition allows it to interact effectively with other compounds, making it a versatile addition to various skincare formulations.

The history of Thiomorpholinone in cosmetics is relatively recent. Initially, it was studied for its potential in pharmaceuticals due to its antioxidant capabilities. Over time, researchers discovered that these same properties could be beneficial in skincare products, leading to its adoption by the cosmetic industry. The compound’s ability to neutralize free radicals and condition the skin made it an attractive option for formulators looking to enhance the efficacy of their products.

Thiomorpholinone is typically synthesized through a series of chemical reactions that involve the introduction of sulfur into a morpholine ring. This process is carried out in controlled laboratory settings to ensure the purity and stability of the final product. The resulting compound is then tested for safety and efficacy before being incorporated into cosmetic formulations.

The Benefits/Uses of Thiomorpholinone

In this section, we will delve into the officially recognized cosmetic benefits and uses of Thiomorpholinone:


Thiomorpholinone acts as an antioxidant, which means it helps to protect your skin from damage caused by free radicals. Free radicals are unstable molecules that can cause oxidative stress, leading to premature aging, fine lines, and wrinkles. By neutralizing these harmful molecules, Thiomorpholinone helps to maintain the skin’s youthful appearance and overall health. In simpler terms, it’s like a shield that helps keep your skin looking fresh and vibrant.

Skin Conditioning

Another key benefit of Thiomorpholinone is its skin conditioning properties. This means it helps to improve the texture and feel of your skin. It works by enhancing the skin’s ability to retain moisture, making it feel softer, smoother, and more supple. Think of it as a moisturizer booster that helps your skin stay hydrated and comfortable throughout the day.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

Thiomorpholinone, while beneficial for its antioxidant and skin conditioning properties, may have some potential side effects and considerations to keep in mind.

  • Skin irritation
  • Redness
  • Itching
  • Allergic reactions

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of thiomorpholinone during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.

Side effects and adverse reactions from thiomorpholinone are generally uncommon. However, as with any cosmetic ingredient, it is recommended to conduct a patch test before widespread usage to ensure there is no adverse reaction.

Thiomorpholinone has a comedogenicity rating of 1, which means it is very unlikely to clog pores. This makes it a suitable option for individuals who are prone to acne, blemishes, or breakouts.

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