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Sh-Oligopeptide-73 Amide Acetate: An In-Depth Look at Its Role in Cosmetics

Article last updated: June 17, 2024

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Ever wondered what makes your favorite skincare products so effective? Dive into the world of Sh-Oligopeptide-73 Amide Acetate and discover its transformative role in cosmetics, from its creation to its impressive benefits and potential side effects.

What is Sh-Oligopeptide-73 Amide Acetate?

Sh-Oligopeptide-73 Amide Acetate is a synthetic ingredient designed to mimic the human protein known as Substance P. This peptide is composed of 11 amino acids, with the C-terminus being an amide, and it includes the proper sequence of the 20 standard amino acids.

The journey of Sh-Oligopeptide-73 Amide Acetate into the cosmetic industry is rooted in the broader exploration of peptides and their benefits for skin health. Initially studied for its role in the nervous system, Substance P was found to have potential applications in skin care due to its ability to influence skin barrier function and inflammation. This led to the development of a synthetic version, Sh-Oligopeptide-73 Amide Acetate, which could be used in topical formulations to harness these benefits.

The production of Sh-Oligopeptide-73 Amide Acetate involves sophisticated synthetic processes. It is created through solid-phase peptide synthesis (SPPS), a method that allows for the precise assembly of amino acids in the correct sequence. This process ensures that the resulting peptide is identical to the naturally occurring Substance P, but with the added stability and consistency required for cosmetic applications. The final product is then converted into its acetate salt form, enhancing its solubility and ease of incorporation into various skincare formulations.

The Benefits/Uses of Sh-Oligopeptide-73 Amide Acetate

In this section, we will delve into the officially recognized cosmetic benefits and uses of Sh-Oligopeptide-73 Amide Acetate:

Skin Conditioning

Sh-Oligopeptide-73 Amide Acetate is known for its skin conditioning properties. This means it helps to maintain the skin in good condition. In practical terms, it can help to keep your skin feeling soft, smooth, and hydrated. By mimicking the natural protein Substance P, it can support the skin’s natural processes, promoting a healthier and more resilient skin barrier. This can be particularly beneficial for those with dry or sensitive skin, as it helps to soothe and nourish the skin, making it look and feel better.

Skin Protecting

Another key benefit of Sh-Oligopeptide-73 Amide Acetate is its ability to protect the skin. This ingredient can help to shield the skin from environmental stressors, such as pollution and UV radiation, which can cause damage and accelerate the aging process. By providing a protective barrier, it helps to prevent these harmful elements from penetrating the skin, thereby reducing the risk of irritation, inflammation, and other skin issues. This protective function is crucial for maintaining overall skin health and preventing premature aging.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

Sh-Oligopeptide-73 Amide Acetate is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind:

  • Skin irritation
  • Redness
  • Allergic reactions

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Sh-Oligopeptide-73 Amide Acetate during pregnancy and breastfeeding are lacking. Therefore, it is recommended that they consult a healthcare professional for further advice before using products containing this ingredient.

Adverse reactions to Sh-Oligopeptide-73 Amide Acetate are generally uncommon, but it is always prudent to perform a patch test before widespread usage to ensure there is no adverse reaction.

In terms of comedogenicity, Sh-Oligopeptide-73 Amide Acetate is rated as a 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating means it is unlikely to clog pores, making it suitable for individuals who are prone to acne, blemishes, or breakouts.

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