Enjoy free tracked US shipping & free returns on all orders. *Ts&Cs apply

Quaternium-72: An In-Depth Look at Its Role in Cosmetics

Article last updated: June 13, 2024

Table of Contents
Ever wondered what makes your favorite cosmetic products so effective? Dive into the world of Quaternium-72 and discover its transformative benefits, how it's made, and what you need to know about potential side effects.

What Is Quaternium-72?

Quaternium-72, also known by its chemical name (Z,Z)-2-(8-Heptadecenyl)-4,5-dihydro-1-methyl-1-[2-[(1-oxo-9-octadecenyl)amino]ethyl]-1H-imidazolium methyl sulphate, is a synthetic ingredient primarily used in the cosmetic industry. It is commonly referred to as an antistatic and hair conditioning agent. This ingredient is part of the quaternary ammonium compounds family, which are known for their conditioning properties.

The history of Quaternium-72 in cosmetics dates back to the mid-20th century when the demand for more effective hair care products began to rise. Scientists were on the lookout for ingredients that could help manage hair static and improve hair texture. Quaternium-72 emerged as a solution due to its unique chemical structure, which allows it to bond with hair fibers, reducing static and enhancing smoothness.

The production of Quaternium-72 involves a series of chemical reactions. It starts with the synthesis of the imidazolium ring, followed by the attachment of the heptadecenyl and octadecenyl chains. The final step involves the addition of the methyl sulfate group, which gives Quaternium-72 its antistatic and conditioning properties. This meticulous process ensures that the ingredient is effective and safe for use in various hair care formulations.

The Benefits/Uses of Quaternium-72

In this section, we will delve into the officially recognized cosmetic benefits and uses of Quaternium-72:


One of the primary benefits of Quaternium-72 is its antistatic property. This means it helps to reduce or eliminate the buildup of static electricity in your hair. If you’ve ever experienced frizzy hair that seems to have a mind of its own, especially in dry or windy conditions, Quaternium-72 can be a game-changer. By neutralizing static charges, it helps to keep your hair smooth and manageable, making it easier to style and less prone to flyaways.

Hair Conditioning

Quaternium-72 also serves as a hair conditioning agent. This means it helps to improve the texture and appearance of your hair, making it feel softer and look shinier. It works by forming a thin, protective layer around each hair strand, which helps to lock in moisture and reduce damage from environmental factors like pollution and UV rays. As a result, your hair can become more resilient, less prone to breakage, and overall healthier-looking.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

Quaternium-72 is generally considered safe for use in cosmetic products, but as with any ingredient, there are potential side effects and considerations to keep in mind.

  • Skin irritation
  • Allergic reactions
  • Contact dermatitis

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Quaternium-72 during pregnancy are lacking. Therefore, it is advisable for pregnant or breastfeeding women to consult a healthcare professional for further advice before using products containing this ingredient.

Adverse reactions to Quaternium-72 are relatively uncommon, but it is always recommended to perform a patch test before widespread usage to ensure there is no sensitivity or allergic reaction.

Quaternium-72 has a comedogenic rating of 1, which means it is considered to be minimally comedogenic. This is good news for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.

Join our newsletter & get 15% off your first Deascal order.
Enjoy free express shipping & free returns on all orders. *Ts&Cs apply
Trending Products
15% Off
Enter your name & email below to get a 15% off coupon sent to your inbox.
uk.deascal.com is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
This site uses cookies to improve your experience. By continuing to browse, you agree to the use of cookies. Read the Privacy Policy here.