Article last updated: October 15, 2024
Nonapeptide-15 Sh-Polypeptide-56 Tripeptide-44 Rh-Oligopeptide-4 is a synthetic fusion peptide that has found its way into the world of cosmetics. This ingredient is a single chain peptide produced through fermentation in E. coli, a common bacterium used in biotechnology for its efficiency in producing complex proteins. The peptide itself is a fusion of four distinct peptides: Nonapeptide-15, Sh-Polypeptide-56, Tripeptide-44, and Rh-Oligopeptide-4. Together, they form a chain of 66 amino acids, composed of the 20 standard amino acids that are the building blocks of proteins.
The journey of Nonapeptide-15 Sh-Polypeptide-56 Tripeptide-44 Rh-Oligopeptide-4 into cosmetics began with advancements in genetic engineering and biotechnology. Scientists synthesized the starting gene by fusing the genes of the four individual peptides. This gene was then introduced into E. coli, which, through fermentation, produced the desired peptide. The result is a highly specific and consistent ingredient that can be used in various cosmetic formulations.
In the realm of cosmetics, this peptide is celebrated for its multifunctional properties. It is primarily known for its roles in hair conditioning, skin conditioning, and skin protecting. However, it’s important to understand what it can and cannot do to avoid being misled by marketing claims. While it offers several benefits, it is not a miracle cure for all skin and hair issues.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Nonapeptide-15 Sh-Polypeptide-56 Tripeptide-44 Rh-Oligopeptide-4:
This ingredient is known for its hair conditioning properties. What does this mean for you? Essentially, it helps to improve the overall texture and appearance of your hair. By incorporating this peptide into hair care products, you can expect smoother, shinier, and more manageable hair. It works by nourishing the hair strands and providing essential proteins that strengthen and protect the hair from damage.
Nonapeptide-15 Sh-Polypeptide-56 Tripeptide-44 Rh-Oligopeptide-4 also serves as a skin conditioning agent. This means it helps to maintain the skin’s softness, suppleness, and overall health. When used in skincare products, it can enhance the skin’s natural barrier, keeping it hydrated and resilient. This peptide works by promoting the production of essential proteins and lipids in the skin, which are crucial for maintaining a healthy and youthful complexion.
Another significant benefit of this ingredient is its skin protecting function. It helps to shield the skin from environmental stressors such as pollution, UV rays, and harsh weather conditions. By forming a protective barrier on the skin’s surface, it minimizes the risk of damage and irritation. This protective layer can also help to prevent the loss of moisture, keeping the skin hydrated and less prone to dryness and sensitivity.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Nonapeptide-15 Sh-Polypeptide-56 Tripeptide-44 Rh-Oligopeptide-4 is generally considered safe for topical application, with a low allergenic potential. However, as with any cosmetic ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data on the topical usage of Nonapeptide-15 Sh-Polypeptide-56 Tripeptide-44 Rh-Oligopeptide-4 during pregnancy is lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice.
Adverse reactions to this ingredient are relatively uncommon, but it is recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Nonapeptide-15 Sh-Polypeptide-56 Tripeptide-44 Rh-Oligopeptide-4 has a rating of 0, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
