Article last updated: October 15, 2024
Nicotiana Benthamiana Rh-Oligopeptide-1, also known as rh-EGF (recombinant human Epidermal Growth Factor), is a fascinating ingredient in the world of cosmetics. This single-chain recombinant human peptide is derived from the Nicotiana benthamiana plant, a relative of the common tobacco plant. The peptide is produced through a sophisticated biotechnological process that involves the transient expression or stable insertion of a human gene into the plant’s DNA. This allows the plant to produce a peptide that is identical to the human epidermal growth factor, which plays a crucial role in skin regeneration and protection.
The journey of Nicotiana Benthamiana Rh-Oligopeptide-1 into the realm of cosmetics is quite intriguing. Initially, the use of recombinant proteins in skincare was limited due to the high costs and complex production methods. However, advancements in plant biotechnology have made it possible to produce these peptides more efficiently and cost-effectively. Nicotiana benthamiana, in particular, has become a popular choice for this purpose due to its rapid growth and ability to express foreign proteins at high levels.
The production process of Nicotiana Benthamiana Rh-Oligopeptide-1 involves inserting a copy of the human gene responsible for epidermal growth factor into the plant’s genome. This can be done either transiently, where the gene is temporarily expressed, or stably, where the gene is permanently integrated into the plant’s DNA. The plant then produces the peptide, which is subsequently extracted and purified for use in cosmetic formulations. This method not only ensures a high degree of purity but also aligns with sustainable and eco-friendly practices, making it a preferred choice for modern skincare products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Nicotiana Benthamiana Rh-Oligopeptide-1:
Nicotiana Benthamiana Rh-Oligopeptide-1 is primarily known for its skin-protecting properties. This means it helps to shield the skin from various environmental stressors, such as pollution, UV radiation, and harsh weather conditions. By forming a protective barrier on the skin’s surface, it can help to maintain the skin’s integrity and prevent damage from external factors. This protective function is crucial for maintaining healthy, resilient skin, especially in urban environments where exposure to pollutants is high.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Nicotiana Benthamiana Rh-Oligopeptide-1 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Nicotiana Benthamiana Rh-Oligopeptide-1 during pregnancy and breastfeeding are lacking. Therefore, it is recommended that they consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Nicotiana Benthamiana Rh-Oligopeptide-1 are generally uncommon. However, it is always advisable to perform a patch test before widespread usage to ensure that the ingredient does not cause any adverse reactions.
In terms of comedogenicity, Nicotiana Benthamiana Rh-Oligopeptide-1 has a rating of 0, meaning it is non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
