Article last updated: October 15, 2024
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 is a unique fusion peptide that has found its way into the world of cosmetics. This ingredient is derived from Nicotiana benthamiana, a plant species closely related to tobacco. The peptide itself is a combination of Hexapeptide-40 and a single chain recombinant human peptide, which is produced by the plant using advanced biotechnological methods such as transient expression systems or transgenesis. Essentially, this means that scientists have inserted a human gene, specifically one that codes for Thioredoxin, into the plant’s DNA to produce this peptide. The resulting fusion peptide consists of 110 amino acids and may include disulfide bonds and glycosylation, ensuring it maintains the proper sequence of the 20 standard amino acids.
The journey of Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 into cosmetics is a fascinating one. Initially, the use of plants like Nicotiana benthamiana in biotechnology was primarily for pharmaceutical purposes, such as producing vaccines and therapeutic proteins. However, the cosmetic industry soon recognized the potential of these plant-derived peptides for skin and hair care. The ability to produce human-like peptides in plants opened up new avenues for creating effective and biocompatible cosmetic ingredients.
The production process of this peptide involves either transient expression, where the gene is temporarily introduced into the plant cells, or transgenesis, where the gene is stably integrated into the plant’s genome. Both methods ensure that the plant can produce the desired peptide in sufficient quantities. Once harvested, the peptide is extracted and purified for use in cosmetic formulations. This innovative approach not only provides a sustainable source of the peptide but also ensures its high purity and consistency, making it a valuable addition to various skincare and haircare products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2:
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 is known for its hair conditioning properties. This means it can help improve the texture and appearance of your hair. When used in hair care products, it can make your hair feel softer, smoother, and more manageable. Essentially, it works to maintain the hair’s natural moisture balance, preventing dryness and brittleness. So, if you’re dealing with frizzy or damaged hair, this ingredient can be a game-changer in your hair care routine.
Another significant benefit of Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 is its ability to condition the skin. This ingredient helps to keep your skin hydrated and supple. It can enhance the skin’s overall appearance by making it feel softer and more elastic. By maintaining the skin’s moisture levels, it can also help reduce the appearance of fine lines and wrinkles, giving your skin a more youthful and radiant look. If you’re looking for a way to boost your skincare regimen, this ingredient is definitely worth considering.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 during pregnancy are lacking. Therefore, it is advisable for pregnant or breastfeeding women to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions to this ingredient are generally uncommon. However, it is recommended to perform a patch test before widespread usage to ensure there is no adverse reaction.
In terms of comedogenicity, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 has a rating of 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating means it is unlikely to clog pores and is generally suitable for people prone to acne, blemishes, or breakouts.
