Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1: An In-Depth Look at Its Role in Cosmetics

What is Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1?

Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 is a fascinating fusion peptide derived from the plant Nicotiana benthamiana. This ingredient is also known in the cosmetic industry as a skin conditioning agent. The peptide is a combination of Hexapeptide-40 and a single chain recombinant human peptide, which is produced by the Nicotiana benthamiana plant through either a transient expression system or transgenesis. Essentially, this means that scientists insert a copy of a human gene, specifically the one that codes for Epidermal Growth Factor (EGF), into the plant’s DNA, allowing it to produce the desired peptide.

The fusion peptide itself is composed of up to 59 amino acids, which may include disulfide bonds and glycosylation, ensuring it mimics the structure and function of natural human peptides. The protein sequence is crafted from the 20 standard amino acids, making it biocompatible and effective for its intended use in skincare.

The journey of Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 into the world of cosmetics is rooted in biotechnological advancements. Initially, the focus was on utilizing plants for the production of pharmaceutical proteins. However, as the technology evolved, the potential for creating high-quality, bioactive peptides for skincare became apparent. Using the plant’s ability to produce complex proteins, researchers were able to develop this innovative ingredient, which has since found its way into various cosmetic formulations aimed at improving skin health and appearance.

The Benefits/Uses of Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1

In this section, we will delve into the officially recognized cosmetic benefits and uses of Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1:

Skin Conditioning

Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition, making it feel smoother, softer, and more hydrated. When applied in cosmetic formulations, it can enhance the overall appearance of the skin, giving it a healthier and more youthful look. The peptide works by interacting with the skin’s natural processes to improve its texture and resilience.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.

• Skin irritation: Some individuals may experience redness, itching, or irritation upon application.
• Allergic reactions: Although rare, allergic reactions such as hives, swelling, or severe itching can occur.
• Contact dermatitis: Prolonged use may lead to contact dermatitis in sensitive individuals.

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 during pregnancy and breastfeeding are lacking. It is advisable for these individuals to consult a healthcare professional for further advice.

Side effects and adverse reactions from this ingredient are generally uncommon. However, it is recommended to perform a patch test before widespread usage to ensure there is no adverse reaction.

In terms of comedogenicity, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 is rated as 0 on a scale of 0 to 5, meaning it is non-comedogenic. This makes it suitable for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.