Article last updated: October 15, 2024
Myristoyl Dipeptide-12 Amide is a synthetic compound derived from the reaction of myristic acid and Dipeptide-12, where the C-terminus of the dipeptide is converted into an amide. Myristic acid is a saturated fatty acid commonly found in nutmeg, palm oil, and coconut oil, while Dipeptide-12 is a small chain of two amino acids. This combination results in a molecule that is both lipid-friendly and peptide-based, making it a versatile ingredient in the cosmetic industry.
The use of Myristoyl Dipeptide-12 Amide in cosmetics is relatively recent, emerging from advancements in peptide technology and the growing demand for multifunctional ingredients. Initially, peptides gained popularity for their anti-aging properties, but researchers soon discovered that combining them with fatty acids could enhance their stability and efficacy. This led to the development of Myristoyl Dipeptide-12 Amide, which offers unique benefits, particularly its antimicrobial properties.
The production process of Myristoyl Dipeptide-12 Amide involves a series of chemical reactions. First, myristic acid is activated, usually by converting it into an acyl chloride. This activated form then reacts with Dipeptide-12, which has been modified to have an amide group at its C-terminus. The reaction typically occurs under controlled conditions to ensure the purity and stability of the final product. The result is a compound that combines the hydrophobic properties of myristic acid with the bioactive potential of the dipeptide, making it an effective ingredient in various cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Myristoyl Dipeptide-12 Amide:
Myristoyl Dipeptide-12 Amide is primarily recognized for its antimicrobial properties. This means it helps to inhibit the growth of microorganisms, such as bacteria and fungi, on the skin. In practical terms, this can be particularly beneficial in products designed to maintain skin hygiene and prevent infections. For example, it can be found in formulations like facial cleansers, body washes, and even some moisturizers, where it helps to keep the skin clean and reduce the risk of breakouts caused by bacterial growth.
Note:
The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Myristoyl Dipeptide-12 Amide is generally considered safe for topical use in cosmetic products. However, like any ingredient, it may cause side effects in some individuals. The potential side effects of topical application of Myristoyl Dipeptide-12 Amide include:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Myristoyl Dipeptide-12 Amide during pregnancy are lacking. Therefore, it is recommended that pregnant or breastfeeding women consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to Myristoyl Dipeptide-12 Amide are relatively uncommon, but it is always prudent to perform a patch test before widespread usage to ensure there is no adverse reaction.
In terms of comedogenicity, Myristoyl Dipeptide-12 Amide has a rating of 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating indicates that it is unlikely to clog pores and is generally suitable for individuals prone to acne, blemishes, or breakouts.
