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Article last updated: October 15, 2024
Hydroxycinnamoyl Dipeptide-27 Amide is a synthetic cosmetic ingredient derived from the reaction of Hydroxycinnamic Acid and Dipeptide-27, where the C-terminus of the peptide is an amide. This compound is known for its skin conditioning and skin protecting properties, making it a popular choice in various skincare formulations.
The ingredient is sometimes referred to by other names, such as Hydroxycinnamoyl Dipeptide or simply Dipeptide-27 Amide, depending on the context in which it is used. Chemically, it combines the antioxidant properties of Hydroxycinnamic Acid with the skin-rejuvenating benefits of a dipeptide, creating a multifunctional compound that can enhance the efficacy of skincare products.
The history of Hydroxycinnamoyl Dipeptide-27 Amide in cosmetics is relatively recent, as advancements in peptide synthesis and cosmetic chemistry have allowed for the creation of more targeted and effective skincare ingredients. Researchers and cosmetic chemists have been exploring the potential of peptides and naturally occurring acids for their ability to improve skin health, leading to the development of this innovative ingredient.
The production process involves a series of chemical reactions where Hydroxycinnamic Acid is first activated and then reacted with Dipeptide-27. The final step involves converting the C-terminus of the peptide into an amide, resulting in Hydroxycinnamoyl Dipeptide-27 Amide. This meticulous process ensures that the ingredient retains its beneficial properties and can be effectively incorporated into various cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Hydroxycinnamoyl Dipeptide-27 Amide:
Hydroxycinnamoyl Dipeptide-27 Amide is known for its skin conditioning properties. This means it helps to maintain the skin in good condition. In practical terms, this ingredient can help to keep your skin feeling soft, smooth, and hydrated. It works by forming a protective barrier on the skin’s surface, which helps to lock in moisture and prevent dryness. This can be particularly beneficial for those with dry or sensitive skin, as it helps to soothe and nourish the skin, making it look and feel healthier.
Another key benefit of Hydroxycinnamoyl Dipeptide-27 Amide is its skin protecting function. This means it helps to shield the skin from external aggressors such as pollution, UV rays, and other environmental stressors. By providing this protective barrier, the ingredient helps to prevent damage to the skin, which can lead to premature aging, irritation, and other skin issues. This protective quality makes it a valuable addition to skincare products aimed at preserving the skin’s natural integrity and youthful appearance.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Hydroxycinnamoyl Dipeptide-27 Amide is generally considered safe for topical use in cosmetic products. However, as with any skincare ingredient, there are potential side effects to be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Hydroxycinnamoyl Dipeptide-27 Amide during pregnancy and breastfeeding are lacking. Therefore, it is advisable to consult a healthcare professional for further advice.
Adverse reactions to Hydroxycinnamoyl Dipeptide-27 Amide are relatively uncommon, but it is always prudent to perform a patch test before widespread usage to ensure individual tolerance.
In terms of comedogenicity, Hydroxycinnamoyl Dipeptide-27 Amide has a rating of 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating suggests that it is unlikely to clog pores, making it suitable for individuals prone to acne, blemishes, or breakouts.
