Article last updated: October 15, 2024
Human Peripheral Blood Derived Natural Killer Cell Conditioned Media, often abbreviated as hPB-NKCM, is a fascinating and somewhat complex ingredient making waves in the cosmetic industry. This ingredient is derived from the growth media used to culture human peripheral blood-derived natural killer (NK) cells. Essentially, after several days of growth, the media in which these NK cells have been cultured is collected and utilized. The starting media is a serum-free stem cell growth medium, ensuring that the final product is free from animal-derived components.
In terms of its chemical composition, hPB-NKCM is rich in a variety of bioactive molecules, including cytokines, growth factors, and other signaling proteins. These components are naturally secreted by the NK cells during their growth phase and are believed to offer numerous benefits when applied to the skin.
The journey of hPB-NKCM into the world of cosmetics is relatively recent. Initially, NK cells and their secretions were primarily studied for their roles in the immune system and potential therapeutic applications, particularly in cancer treatment. However, as research progressed, scientists began to uncover the potential skin benefits of the bioactive molecules secreted by these cells. This led to the innovative idea of incorporating the conditioned media into skincare products, aiming to harness its skin conditioning and protecting properties.
The production process of hPB-NKCM involves several meticulous steps. First, peripheral blood is collected from healthy human donors. The NK cells are then isolated and cultured in a specialized serum-free stem cell growth medium. Over several days, these cells grow and secrete various beneficial molecules into the media. Once the growth period is complete, the conditioned media is carefully harvested, filtered, and prepared for inclusion in cosmetic formulations. This ensures that the final product is both potent and safe for topical application.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Human Peripheral Blood Derived Natural Killer Cell Conditioned Media:
One of the primary benefits of Human Peripheral Blood Derived Natural Killer Cell Conditioned Media is its skin conditioning properties. This means that the ingredient helps to maintain the skin in good condition. In practical terms, it can make your skin feel softer, smoother, and more hydrated. By enhancing the overall texture and appearance of the skin, it can contribute to a more youthful and radiant complexion.
Another significant benefit is its ability to protect the skin. This function involves shielding the skin from environmental stressors and potential damage. By fortifying the skin’s natural barrier, it helps to prevent issues like dryness, irritation, and premature aging. Essentially, it acts as a defensive layer, ensuring that your skin remains healthy and resilient against external aggressors.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Human Peripheral Blood Derived Natural Killer Cell Conditioned Media is generally considered safe for topical use in cosmetics. However, as with any ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Human Peripheral Blood Derived Natural Killer Cell Conditioned Media during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from this ingredient are generally uncommon, but they can occur. It is recommended to perform a patch test before widespread usage to ensure there is no adverse reaction.
The comedogenicity of Human Peripheral Blood Derived Natural Killer Cell Conditioned Media is rated at 0, meaning it is considered non-comedogenic. This is beneficial for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
