Article last updated: October 15, 2024
Human Keratinocytes are the principal cells found in the human epidermis, the outermost layer of the skin. These cells play a crucial role in the protective barrier function of the skin. In the context of cosmetics, Human Keratinocytes are often used for their skin conditioning properties, helping to maintain and improve the skin’s appearance and texture.
The source of Human Keratinocytes is, as the name suggests, human skin. These cells are typically derived from cultured human epidermal cells. In some cases, they might be referred to by other names such as epidermal keratinocytes or simply keratinocytes. Chemically, these cells are rich in keratin, a type of protein that provides structural strength to the skin, hair, and nails.
The use of Human Keratinocytes in cosmetics has a relatively recent history. Advances in cell culture technology have made it possible to grow these cells in laboratory settings, allowing for their inclusion in various skincare products. Initially, the focus was on medical applications, particularly in wound healing and skin grafting. However, as the benefits of these cells became more apparent, the cosmetic industry began to explore their potential for enhancing skin health and appearance.
The process of making Human Keratinocytes for cosmetic use involves isolating these cells from human skin samples and then cultivating them in controlled laboratory environments. This ensures that the cells are viable and retain their beneficial properties. Once cultured, the cells can be incorporated into various formulations, such as creams, serums, and masks, to deliver their skin conditioning benefits.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Human Keratinocytes:
Human Keratinocytes are primarily known for their skin conditioning properties. This means they help to maintain the skin’s softness, smoothness, and overall health. When included in cosmetic formulations, these cells can enhance the skin’s natural barrier function, ensuring it stays hydrated and resilient against environmental stressors. Essentially, they help your skin look and feel its best by supporting its natural functions.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Human Keratinocytes are generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Human Keratinocytes during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Human Keratinocytes are relatively uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure that your skin does not react adversely to the ingredient.
In terms of comedogenicity, Human Keratinocytes have a rating of 0 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means that Human Keratinocytes are unlikely to clog pores and are generally suitable for people prone to acne, blemishes, or breakouts.
