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Dioleoyl Edetolmonium Methosulfate: An In-Depth Look at Its Role in Cosmetics

Article last updated: June 13, 2024

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Ever wondered what makes your favorite skincare products so effective? Dive into the fascinating world of Dioleoyl Edetolmonium Methosulfate and discover its transformative role in cosmetics, from its creation to its myriad benefits and potential side effects.

What Is Dioleoyl Edetolmonium Methosulfate?

Dioleoyl Edetolmonium Methosulfate, also known by its more complex chemical name 1-Propanaminium, 2-hydroxy-N-[2-[(2-hydroxypropyl) [2-[(1-oxo-9-octadecenyl)oxy]propyl]amino]ethyl]-N-methyl-N-[2-[(1-oxo-9-octadecenyl)oxy]propyl]-, methyl sulfate (salt), is a multifaceted ingredient commonly found in various cosmetic products. This compound is primarily derived from oleic acid, a fatty acid that is prevalent in many natural oils such as olive oil and sunflower oil. Its chemical composition includes multiple functional groups that contribute to its versatility in cosmetic formulations.

The history of Dioleoyl Edetolmonium Methosulfate in cosmetics is relatively recent, emerging as a response to the growing demand for multifunctional ingredients that can enhance the performance of beauty products. Initially, it was developed to address the need for more effective conditioning agents in hair care products. Over time, its unique properties have made it a staple in a variety of formulations, from shampoos and conditioners to skin cleansers and emulsions.

The production of Dioleoyl Edetolmonium Methosulfate involves a series of chemical reactions that start with the esterification of oleic acid. This process is followed by quaternization, where the compound is treated with a methylating agent to form the final quaternary ammonium compound. The resulting product is then purified and stabilized, making it suitable for use in cosmetic applications. This meticulous manufacturing process ensures that the ingredient maintains its efficacy and safety, providing consistent results in various formulations.

The Benefits/Uses of Dioleoyl Edetolmonium Methosulfate

In this section, we will delve into the officially recognized cosmetic benefits and uses of Dioleoyl Edetolmonium Methosulfate:


One of the key benefits of Dioleoyl Edetolmonium Methosulfate is its antistatic properties. This means it helps to reduce static electricity, which can make hair more manageable and less frizzy. If you’ve ever experienced flyaway hairs or that annoying static cling, this ingredient can help keep your hair smooth and in place.


Dioleoyl Edetolmonium Methosulfate also acts as a buffering agent. In simple terms, it helps to maintain the pH balance of cosmetic products. This is crucial because a balanced pH ensures that the product is gentle on your skin and hair, reducing the risk of irritation and making the product more effective overall.

Hair Conditioning

Another significant benefit is its hair conditioning capability. This ingredient helps to soften and smooth the hair, making it easier to comb and style. It can improve the overall texture and appearance of your hair, leaving it feeling silky and looking shiny.


Dioleoyl Edetolmonium Methosulfate also has cleansing properties. It helps to remove dirt, oil, and other impurities from the hair and scalp. This makes it a valuable ingredient in shampoos and other cleansing products, ensuring that your hair feels fresh and clean after use.


Lastly, this ingredient serves as an emulsifying agent. This means it helps to blend oil and water-based ingredients together, creating a stable and uniform product. This is particularly important in creams, lotions, and other formulations where a consistent texture and performance are desired.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

Dioleoyl Edetolmonium Methosulfate is generally considered safe for use in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.

  • Skin irritation
  • Allergic reactions
  • Contact dermatitis

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Dioleoyl Edetolmonium Methosulfate during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.

Adverse reactions to Dioleoyl Edetolmonium Methosulfate are relatively uncommon, but they can occur. It is recommended to conduct a patch test before widespread usage to ensure that you do not have an adverse reaction to the ingredient.

In terms of comedogenicity, Dioleoyl Edetolmonium Methosulfate has a rating of 2 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means it has a low to moderate likelihood of clogging pores. Individuals who are prone to acne, blemishes, or breakouts should be cautious when using products containing this ingredient, as it may contribute to pore congestion in some cases.

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