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Choleth-24: An In-Depth Look at Its Role in Cosmetics

Article last updated: June 13, 2024

Table of Contents
Ever wondered what makes your favorite skincare products so effective? Dive into our comprehensive guide on Choleth-24, uncovering its origins, benefits, and potential side effects, and discover why this ingredient is a game-changer in the world of cosmetics.

What is Choleth-24?

Choleth-24, also known by its chemical name (3beta)-Cholest-5-en-3-ol, ethoxylated (24 mol EO average molar ratio), is a versatile ingredient commonly found in various cosmetic and personal care products. Derived from cholesterol, a natural substance found in animal cells, Choleth-24 is a type of ethoxylated alcohol. The “24” in its name indicates that it has been ethoxylated with an average of 24 moles of ethylene oxide, a process that enhances its solubility and functionality in formulations.

The use of Choleth-24 in cosmetics has a relatively recent history, emerging as a response to the growing demand for more effective and stable emulsifiers and cleansing agents. Its ability to blend oil and water-based ingredients seamlessly has made it a popular choice among formulators. The ethoxylation process, which involves the addition of ethylene oxide to cholesterol, results in a compound that can effectively reduce surface tension, making it easier to remove dirt and oil from the skin.

Choleth-24 is primarily produced through a chemical reaction that starts with cholesterol. This cholesterol is subjected to ethoxylation, where ethylene oxide is added in a controlled manner to achieve the desired molar ratio. The result is a compound that retains the beneficial properties of cholesterol while gaining new functionalities that make it suitable for use in a wide range of cosmetic products.

The Benefits/Uses of Choleth-24

In this section, we will delve into the officially recognized cosmetic benefits and uses of Choleth-24:


Choleth-24 is an effective cleansing agent. This means it helps to remove dirt, oil, and other impurities from the skin. When included in a cosmetic product, it works by breaking down and emulsifying the oils and grime on your skin, making it easier to wash them away. This can leave your skin feeling fresh, clean, and free from unwanted residues.


Another key benefit of Choleth-24 is its emulsifying property. In simple terms, it helps to mix ingredients that typically don’t blend well together, like oil and water. This is crucial for creating stable and uniform cosmetic formulations, such as creams, lotions, and serums. By ensuring that all the ingredients are evenly distributed, Choleth-24 helps to maintain the consistency and effectiveness of the product throughout its shelf life.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

Choleth-24 is generally considered safe for use in cosmetic products, but like any ingredient, it can have potential side effects and considerations that users should be aware of.

  • Skin irritation
  • Allergic reactions
  • Contact dermatitis

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Choleth-24 during pregnancy and breastfeeding are lacking. Therefore, it is recommended that they consult a healthcare professional for further advice before using products containing this ingredient.

Side effects and adverse reactions from Choleth-24 are relatively uncommon. However, as with any cosmetic ingredient, it is advisable to conduct a patch test before widespread usage to ensure there is no adverse reaction.

Choleth-24 has a comedogenic rating of 2 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means that it has a low to moderate potential to clog pores. Individuals who are prone to acne, blemishes, or breakouts should be cautious when using products containing this ingredient.

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