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C18-22 Isoalkylamidopropylethyldimonium Ethosulfate: An In-Depth Look at Its Role in Cosmetics

Article last updated: June 13, 2024

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Ever wondered what makes your favorite cosmetics so effective? Dive into the science behind C18-22 Isoalkylamidopropylethyldimonium Ethosulfate and discover its transformative benefits, production process, and potential side effects in our comprehensive guide.

What is C18-22 Isoalkylamidopropylethyldimonium Ethosulfate?

C18-22 Isoalkylamidopropylethyldimonium Ethosulfate, also known by its more technical name 1-Propanaminium, N-ethyl-N,N-dimethyl-3-[(1-oxo-C18-22-alkyl)amino]-, ethyl sulfate (salt), is a synthetic ingredient commonly used in cosmetic products. This ingredient is primarily sourced from fatty acids derived from natural oils, such as coconut or palm oil, which are then chemically modified to produce the final compound.

The history of C18-22 Isoalkylamidopropylethyldimonium Ethosulfate in cosmetics dates back to the increasing demand for more effective hair conditioning agents. As consumers sought products that could provide better manageability and softness without weighing down the hair, chemists developed this compound to meet those needs. Its unique structure allows it to act as an antistatic and hair conditioning agent, making it a popular choice in formulations for shampoos, conditioners, and other hair care products.

The manufacturing process of C18-22 Isoalkylamidopropylethyldimonium Ethosulfate involves several steps. Initially, fatty acids from natural oils are converted into fatty amides. These fatty amides are then reacted with propylene oxide to form the intermediate compound. Finally, this intermediate is quaternized with ethyl sulfate to produce the final ingredient. This multi-step synthesis ensures that the compound is both effective and safe for use in cosmetic products.

The Benefits/Uses of C18-22 Isoalkylamidopropylethyldimonium Ethosulfate

In this section, we will delve into the officially recognized cosmetic benefits and uses of C18-22 Isoalkylamidopropylethyldimonium Ethosulfate:


One of the primary benefits of C18-22 Isoalkylamidopropylethyldimonium Ethosulfate is its antistatic properties. This means that it helps to reduce or eliminate static electricity in your hair. If you’ve ever experienced the frustration of flyaway hairs or hair that clings to your clothes, you’ll appreciate this benefit. By neutralizing static charges, this ingredient helps keep your hair smooth and manageable, making it easier to style and maintain throughout the day.

Hair Conditioning

Another significant benefit of C18-22 Isoalkylamidopropylethyldimonium Ethosulfate is its hair conditioning capability. This ingredient works to improve the texture and appearance of your hair by making it softer and more supple. It helps to detangle hair, reducing breakage and making it easier to comb through. Additionally, it can enhance the overall feel of your hair, leaving it feeling silky and smooth to the touch. This conditioning effect can be particularly beneficial for those with dry or damaged hair, as it helps to restore moisture and vitality.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

C18-22 Isoalkylamidopropylethyldimonium Ethosulfate is generally considered safe for use in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.

  • Skin irritation: Some individuals may experience mild irritation, especially those with sensitive skin.
  • Allergic reactions: Although rare, allergic reactions such as redness, itching, or swelling can occur.
  • Contact dermatitis: In some cases, prolonged use may lead to contact dermatitis, characterized by redness, itching, and inflammation.

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of C18-22 Isoalkylamidopropylethyldimonium Ethosulfate during pregnancy are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.

Adverse reactions to this ingredient are uncommon, but it is always a good practice to perform a patch test before widespread usage to ensure there are no adverse reactions.

In terms of comedogenicity, C18-22 Isoalkylamidopropylethyldimonium Ethosulfate has a rating of 1 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This low rating means it is unlikely to clog pores and is generally suitable for people prone to acne, blemishes, or breakouts.

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