Article last updated: October 15, 2024
Acetyl Sh-Tripeptide-3 Amide, also known as Acetyl Tetrapeptide-3, is a synthetic peptide that has gained popularity in the cosmetic industry for its skin conditioning properties. This ingredient is derived from the acetylation of Sh-Tripeptide-3, a process that involves adding an acetyl group to the tripeptide, with the C-terminus being an amide. This modification enhances the stability and efficacy of the peptide, making it more suitable for use in skincare formulations.
The history of Acetyl Sh-Tripeptide-3 Amide in cosmetics is relatively recent, as advancements in peptide synthesis and biotechnology have allowed for the development of more sophisticated and targeted skincare ingredients. Initially, peptides were primarily studied for their roles in biological processes and medical applications. However, as research progressed, their potential benefits for skin health and appearance became evident, leading to their incorporation into cosmetic products.
The production of Acetyl Sh-Tripeptide-3 Amide involves a series of chemical reactions starting with the synthesis of the base tripeptide. This tripeptide is then acetylated, a process that introduces an acetyl group to the molecule, enhancing its stability and bioavailability. The final step involves converting the C-terminus to an amide, which further refines the peptide for optimal performance in skincare applications. This meticulous process ensures that the resulting ingredient is both effective and safe for use in various cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Acetyl Sh-Tripeptide-3 Amide:
Acetyl Sh-Tripeptide-3 Amide is primarily known for its skin conditioning properties. In simpler terms, this means that the ingredient helps to maintain the skin in good condition. It works by enhancing the appearance and feel of the skin, making it softer, smoother, and more supple. This can be particularly beneficial for those with dry or rough skin, as it helps to restore a healthy and hydrated look. By incorporating products containing this ingredient into your skincare routine, you can expect your skin to feel more nourished and revitalized.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Acetyl Sh-Tripeptide-3 Amide is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Acetyl Sh-Tripeptide-3 Amide during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions to Acetyl Sh-Tripeptide-3 Amide are generally uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure that your skin does not react negatively to the ingredient.
In terms of comedogenicity, Acetyl Sh-Tripeptide-3 Amide has a rating of 0, meaning it is considered non-comedogenic. This is particularly beneficial for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
