Article last updated: October 15, 2024
Acetyl Hexapeptide-68 Amide Acetate is a synthetic peptide used primarily in cosmetic products for its skin conditioning properties. Chemically, it is the acetate salt of the product obtained by the acetylation of Hexapeptide-68, where the C-terminus of the peptide is an amide. This ingredient is also known by other names, such as AHA-68 and Acetyl Hexapeptide-68.
The history of Acetyl Hexapeptide-68 Amide Acetate in cosmetics is relatively recent, as it emerged from advancements in peptide technology and skin science. Peptides have been increasingly popular in skincare due to their ability to mimic natural processes in the skin, and Acetyl Hexapeptide-68 Amide Acetate is no exception. Researchers discovered that by modifying the peptide structure through acetylation, they could enhance its stability and efficacy, making it a valuable addition to skincare formulations.
The production of Acetyl Hexapeptide-68 Amide Acetate involves a series of complex chemical reactions. Initially, Hexapeptide-68 is synthesized through solid-phase peptide synthesis (SPPS), a method that allows for the precise assembly of amino acids into the desired peptide sequence. Following this, the peptide undergoes acetylation, a chemical process where an acetyl group is introduced to the molecule. Finally, the peptide is converted into its acetate salt form, which improves its solubility and stability, making it suitable for use in various cosmetic products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Acetyl Hexapeptide-68 Amide Acetate:
Acetyl Hexapeptide-68 Amide Acetate is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition, making it feel softer, smoother, and more hydrated. When used in cosmetic formulations, this ingredient can enhance the overall texture and appearance of the skin, giving it a more youthful and radiant look. Essentially, it works by supporting the skin’s natural barrier, helping it to retain moisture and protect against environmental stressors.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Acetyl Hexapeptide-68 Amide Acetate is generally considered safe for topical application in cosmetic products. However, as with any skincare ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Acetyl Hexapeptide-68 Amide Acetate during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Acetyl Hexapeptide-68 Amide Acetate are relatively uncommon. However, it is recommended to conduct a patch test before widespread usage to ensure that your skin does not react negatively to the ingredient.
In terms of comedogenicity, Acetyl Hexapeptide-68 Amide Acetate has a rating of 0 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means that it is unlikely to clog pores and is generally suitable for people prone to acne, blemishes, or breakouts.
