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1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate: An In-Depth Look at Its Role in Cosmetics

Article last updated: June 12, 2024

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Ever wondered what makes your favorite skincare products so effective? Dive into the fascinating world of 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate and discover its transformative role in cosmetics, from its creation to its incredible benefits and potential side effects.

What is 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate?

1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate, also known by its chemical name Pyrimidinium, 2,3-dihydro-1,3,4,6-tetramethyl-2-oxo-, sulfate (1:1), is a synthetic compound primarily used in the cosmetic industry for hair dyeing purposes. This ingredient is a derivative of pyrimidone, a heterocyclic organic compound, and is characterized by the presence of four methyl groups attached to the pyrimidone ring, along with a sulfate group that enhances its solubility and stability in aqueous solutions.

The history of 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate in cosmetics dates back to the mid-20th century when chemists began exploring various pyrimidone derivatives for their potential applications in hair dye formulations. Its unique chemical structure allows it to interact effectively with hair fibers, providing vibrant and long-lasting color. Over the years, it has become a staple ingredient in many commercial hair dye products due to its efficacy and relatively low cost of production.

The manufacturing process of 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate involves several chemical synthesis steps. Initially, the base pyrimidone compound is methylated using methylating agents to introduce the four methyl groups. This intermediate product is then reacted with sulfuric acid to form the sulfate salt. The final product is purified through crystallization or other separation techniques to ensure its quality and consistency for use in cosmetic formulations.

The Benefits/Uses of 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate

In this section, we will delve into the officially recognized cosmetic benefits and uses of 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate:

Hair Dyeing

1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate is primarily used in cosmetics for its hair dyeing capabilities. This ingredient acts as a dye precursor, which means it helps in the formation of the final color when applied to hair. When mixed with other components in hair dye formulations, it helps achieve a wide range of vibrant and long-lasting colors. This makes it a valuable ingredient for those looking to change or enhance their hair color, providing a reliable and effective solution for both temporary and permanent hair dye products.

Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).

Potential Side Effects & Other Considerations

1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate is generally considered safe for use in cosmetic products, particularly for its primary function as a hair dyeing agent. However, like any cosmetic ingredient, it may pose certain risks and considerations.

  • Skin irritation
  • Allergic reactions
  • Contact dermatitis

Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.

Side effects and adverse reactions from this ingredient are relatively uncommon, but they can occur. It is recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.

In terms of comedogenicity, 1,3,4,6-Tetramethyl-2-Pyrimidone Sulfate has a rating of 0, meaning it is considered non-comedogenic. This is beneficial for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.

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