Article last updated: October 15, 2024
Nonapeptide-16 is a synthetic peptide composed of the amino acids: cysteine, leucine, lysine, phenylalanine, proline, serine, threonine, tyrosine, and valine. In the realm of cosmetics, it is primarily recognized for its skin conditioning properties.
The journey of Nonapeptide-16 into the world of cosmetics is rooted in advancements in peptide synthesis and biotechnology. Initially, peptides like Nonapeptide-16 were studied for their potential in medical applications, particularly in wound healing and tissue regeneration. Over time, researchers discovered that these peptides could also offer significant benefits for skin health, leading to their incorporation into cosmetic products.
Nonapeptide-16 is synthesized through a process known as solid-phase peptide synthesis (SPPS). This method involves the sequential addition of amino acids to a growing peptide chain, anchored to a solid resin. Each amino acid is carefully protected and activated to ensure precise bonding, resulting in a highly pure and specific peptide sequence. Once the peptide chain is complete, it is cleaved from the resin and purified, ready to be formulated into various skincare products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Nonapeptide-16:
Nonapeptide-16 is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition, making it feel smoother, softer, and more hydrated. When applied in cosmetic formulations, Nonapeptide-16 can enhance the overall texture and appearance of the skin, giving it a more youthful and radiant look. It works by supporting the skin’s natural functions, ensuring it remains healthy and resilient against environmental stressors.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Nonapeptide-16 is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Nonapeptide-16 during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Adverse reactions to Nonapeptide-16 are relatively uncommon, but it is always prudent to conduct a patch test before widespread use to ensure there is no sensitivity or allergic reaction.
Nonapeptide-16 has a comedogenic rating of 0, meaning it is considered non-comedogenic. This makes it a suitable option for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate such conditions.
