Article last updated: October 15, 2024
Nicotinamide Mononucleotide, also known as Niacinamide Mononucleotide, Niacinamide Ribonucleotide, or Pyridinium, 3-(aminocarbonyl)-1-(5-O-phosphono-\b-D-ribofuranosyl)-, inner salt, is a fascinating ingredient in the world of cosmetics. This compound is derived from niacin, a form of Vitamin B3, and is a nucleotide composed of a nicotinamide base, a ribose sugar, and a phosphate group.
Historically, Nicotinamide Mononucleotide (NMN) has been studied extensively for its potential health benefits, particularly in the realm of anti-aging and cellular repair. Its journey into the cosmetic industry is relatively recent, driven by its potent antioxidant properties. Researchers discovered that NMN could help protect skin cells from oxidative stress, which is a major contributor to skin aging and damage.
The production of NMN typically involves a biosynthetic process where nicotinamide is phosphorylated to form NMN. This can be achieved through enzymatic reactions in a laboratory setting, ensuring a high purity of the final product. The ability to synthesize NMN efficiently has paved the way for its inclusion in various skincare formulations, promising to deliver its antioxidant benefits directly to the skin.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Nicotinamide Mononucleotide:
Nicotinamide Mononucleotide is primarily recognized for its antioxidant properties. But what does this mean for your skin? Antioxidants are like the unsung heroes of skincare. They help to neutralize free radicals, which are unstable molecules that can cause damage to your skin cells. This damage can lead to premature aging, such as fine lines, wrinkles, and loss of elasticity. By incorporating products with Nicotinamide Mononucleotide, you are essentially giving your skin a shield against these harmful elements, helping to maintain a youthful and healthy appearance.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Nicotinamide Mononucleotide is generally considered safe for topical application, but as with any cosmetic ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Nicotinamide Mononucleotide during pregnancy and breastfeeding are lacking. Therefore, it is advisable to consult a healthcare professional for further advice.
Side effects and adverse reactions from this ingredient are generally uncommon. However, it is recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
On a comedogenicity scale of 0 to 5, Nicotinamide Mononucleotide is rated as 0, meaning it is non-comedogenic. This makes it suitable for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
