Article last updated: October 15, 2024
Nicotinamide Adenine Dinucleotide, often abbreviated as NAD+, is a coenzyme found in all living cells. In the context of cosmetics, it is known for its skin conditioning properties. Chemically, it is referred to as Adenosine 5′-(trihydrogen diphosphate), 5′->5′-ester with 3-(aminocarbonyl)-1-beta-D-ribofuranosylpyridinium hydroxide, inner salt. This might sound like a mouthful, but essentially, NAD+ is a complex molecule that plays a crucial role in cellular metabolism and energy production.
The journey of NAD+ into the world of cosmetics is quite fascinating. Initially discovered in the early 20th century, NAD+ was primarily studied for its role in cellular processes and energy metabolism. Over time, researchers began to uncover its potential benefits for skin health, leading to its incorporation into skincare products. The realization that NAD+ could help improve skin texture, reduce the appearance of fine lines, and enhance overall skin vitality made it a sought-after ingredient in the beauty industry.
NAD+ is typically produced through a biosynthetic pathway involving the amino acid tryptophan or the vitamin niacin (vitamin B3). This process can be replicated in a laboratory setting to create a stable form of NAD+ suitable for use in cosmetic formulations.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Nicotinamide Adenine Dinucleotide:
Nicotinamide Adenine Dinucleotide (NAD) is primarily recognized for its skin conditioning properties. This means it helps to maintain the skin in good condition by improving its appearance and texture. When used in cosmetic formulations, NAD can enhance the skin’s overall health, making it look more vibrant and youthful. It works by supporting the skin’s natural processes, helping to keep it hydrated, smooth, and resilient against environmental stressors.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Nicotinamide Adenine Dinucleotide (NAD) is generally considered safe for topical application in cosmetic products. However, as with any skincare ingredient, there are potential side effects and considerations to be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Nicotinamide Adenine Dinucleotide during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Nicotinamide Adenine Dinucleotide are generally uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure that your skin does not react negatively to the ingredient.
In terms of comedogenicity, Nicotinamide Adenine Dinucleotide has a rating of 0, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
