Article last updated: October 15, 2024
Acetyl Sh-Tetrapeptide-1, also known as Acetyl Tetrapeptide-1, is a synthetic peptide that has gained popularity in the cosmetic industry for its skin conditioning properties. This ingredient is derived from the acetylation of Sh-Tetrapeptide-1, a process that involves introducing an acetyl group to the peptide, thereby enhancing its stability and effectiveness. Chemically, it is composed of a sequence of four amino acids, making it a tetrapeptide, which is then modified with an acetyl group.
The history of Acetyl Sh-Tetrapeptide-1 in cosmetics is relatively recent, emerging as a result of advancements in peptide technology and a growing interest in bioactive ingredients that can deliver targeted skin benefits. Initially, peptides were primarily used in medical research, but their potential for skin care applications quickly became apparent. Researchers discovered that certain peptides could mimic natural skin processes, leading to improved skin health and appearance. This led to the development and incorporation of Acetyl Sh-Tetrapeptide-1 into various skincare formulations.
The manufacturing process of Acetyl Sh-Tetrapeptide-1 involves synthesizing the peptide chain through solid-phase peptide synthesis (SPPS). This method allows for precise control over the sequence of amino acids, ensuring the production of a high-purity peptide. Once the tetrapeptide is synthesized, it undergoes acetylation, where an acetyl group is chemically bonded to the peptide. This modification not only enhances the peptide’s stability but also improves its ability to penetrate the skin, making it more effective as a skin conditioning agent.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Acetyl Sh-Tetrapeptide-1:
Acetyl Sh-Tetrapeptide-1 is primarily known for its skin conditioning properties. This means that it helps to maintain the skin in good condition. In practical terms, this ingredient can help to improve the overall appearance and feel of your skin. It works by enhancing the skin’s natural barrier function, which can lead to a smoother, more hydrated complexion. This makes it a popular choice in products aimed at moisturizing and revitalizing the skin.
Note: The listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Acetyl Sh-Tetrapeptide-1 is generally considered safe for topical application in cosmetic products. However, as with any skincare ingredient, there are potential side effects and considerations to keep in mind:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Acetyl Sh-Tetrapeptide-1 during pregnancy and breastfeeding are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions to Acetyl Sh-Tetrapeptide-1 are generally uncommon. However, it is always recommended to perform a patch test before widespread usage to ensure that your skin does not react negatively to the ingredient.
In terms of comedogenicity, Acetyl Sh-Tetrapeptide-1 is rated as 0 on a scale of 0 to 5, where 0 is totally non-comedogenic and 5 is highly comedogenic. This means that it is unlikely to clog pores and is generally suitable for individuals prone to acne, blemishes, or breakouts.
