Article last updated: October 15, 2024
Acetyl Hexapeptide-71 Amide is a synthetic peptide that has garnered attention in the cosmetic industry for its skin conditioning properties. Chemically, it is derived from Hexapeptide-71 through a process known as acetylation, where an acetyl group is introduced to the peptide, and the C-terminus is modified to form an amide. This modification enhances its stability and effectiveness when applied to the skin.
Its development is rooted in the growing interest in peptide-based skincare solutions, which began gaining traction in the early 2000s. Researchers discovered that peptides, which are short chains of amino acids, could play a significant role in skin health by mimicking the body’s natural processes.
The production of Acetyl Hexapeptide-71 Amide involves sophisticated laboratory techniques. Initially, Hexapeptide-71 is synthesized through solid-phase peptide synthesis (SPPS), a method that allows for the precise assembly of amino acids in a specific sequence. Following this, the peptide undergoes acetylation, a chemical reaction that introduces an acetyl group to the molecule, enhancing its stability and making it more suitable for topical application. The final step involves converting the C-terminus to an amide, further improving the peptide’s skin conditioning capabilities.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Acetyl Hexapeptide-71 Amide:
Acetyl Hexapeptide-71 Amide is primarily known for its skin conditioning properties. This means it helps to maintain the skin in good condition, making it feel softer, smoother, and more hydrated. When included in skincare products, it can enhance the overall texture and appearance of the skin, giving it a healthier and more youthful look. Essentially, it works to improve the skin’s natural barrier function, which can be beneficial for all skin types, especially those that are dry or sensitive.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Acetyl Hexapeptide-71 Amide is generally considered safe for topical use in cosmetic products. However, as with any skincare ingredient, it is important to be aware of potential side effects and other considerations.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Acetyl Hexapeptide-71 Amide during pregnancy are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from Acetyl Hexapeptide-71 Amide are generally uncommon. However, it is recommended to conduct a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Acetyl Hexapeptide-71 Amide is rated as a 0 on a scale of 0 to 5, meaning it is considered non-comedogenic. This makes it suitable for individuals who are prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
