Article last updated: October 15, 2024
Distearoyl Glycerophosphocholine, often abbreviated as DSGPC, is a synthetic compound primarily used in the cosmetic industry for its skin conditioning properties. Chemically, it is known as 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt, 4-oxide, (7R)-. This mouthful of a name reflects its complex molecular structure, which includes glycerophosphocholine bonded with two stearic acid molecules.
The origins of DSGPC in cosmetics can be traced back to the increasing demand for ingredients that provide effective skin conditioning without adverse effects. Initially, natural phospholipids were used, but their instability and high cost led to the development of synthetic alternatives like DSGPC. Over time, advancements in chemical synthesis and a better understanding of skin physiology have made DSGPC a popular choice in modern skincare formulations.
The production of Distearoyl Glycerophosphocholine involves a multi-step chemical process. It starts with the esterification of glycerol with stearic acid to form distearoyl glycerol. This intermediate is then reacted with phosphocholine to produce the final compound. The process is carefully controlled to ensure high purity and consistency, making DSGPC a reliable ingredient in various cosmetic products.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Distearoyl Glycerophosphocholine:
Distearoyl Glycerophosphocholine is primarily recognized for its skin conditioning properties. This means it helps to maintain the skin in good condition. When used in cosmetic formulations, it works to improve the appearance and feel of the skin. It can make the skin feel softer, smoother, and more supple. This is particularly beneficial for those with dry or rough skin, as it helps to restore a healthy texture and appearance.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Distearoyl Glycerophosphocholine is generally considered safe for topical application in cosmetic products. However, as with any ingredient, there are potential side effects and considerations to keep in mind.
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Distearoyl Glycerophosphocholine during pregnancy are lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice.
Side effects and adverse reactions from Distearoyl Glycerophosphocholine are generally uncommon. However, it is recommended to perform a patch test before widespread usage to ensure that your skin does not react negatively to the ingredient.
Distearoyl Glycerophosphocholine has a comedogenic rating of 1, which means it is unlikely to clog pores and cause acne or breakouts. This makes it a suitable ingredient for individuals who are prone to acne, blemishes, or breakouts.
