Article last updated: October 15, 2024
Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3, often referred to by its more manageable shorthand names in the industry, is a synthetic fusion peptide designed for use in cosmetic products. This ingredient is a single chain peptide produced through fermentation in E. coli bacteria. The creation process starts with the synthesis of a gene that combines segments from sh-Polypeptide-56, sh-Polypeptide-3, Octapeptide-12, and Tripeptide-44. The result is a fused peptide that contains 186 amino acids, all derived from the 20 standard amino acids commonly found in proteins.
The history of Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3 in cosmetics is relatively recent, as advancements in biotechnology have allowed for the precise engineering of peptides to target specific skin concerns. Initially, peptides were explored for their potential in medical applications, but their ability to interact with skin cells and promote various beneficial effects quickly caught the attention of the cosmetic industry. This particular peptide blend was developed to harness the skin conditioning and protecting properties of its constituent peptides, making it a valuable addition to skincare formulations.
The production of Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3 involves a sophisticated biotechnological process. Scientists first design and synthesize the gene that encodes the desired peptide sequence. This gene is then introduced into E. coli bacteria, which act as tiny bio-factories to produce the peptide through fermentation. Once the bacteria have produced sufficient quantities of the peptide, it is extracted, purified, and prepared for inclusion in cosmetic products. This method ensures a high degree of purity and consistency, which is crucial for maintaining the efficacy and safety of the ingredient in skincare applications.
In this section, we will delve into the officially recognized cosmetic benefits and uses of Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3:
One of the primary benefits of Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3 is its skin conditioning properties. This means that the ingredient helps to maintain the skin in good condition. It works by improving the appearance and feel of the skin, making it softer, smoother, and more supple. Essentially, it helps to keep your skin looking and feeling healthy, which is a fundamental aspect of any skincare routine.
Another significant benefit of this ingredient is its skin protecting function. This means that it helps to shield the skin from various environmental stressors and potential damage. By forming a protective barrier on the skin’s surface, it can help to prevent moisture loss and protect against harmful elements such as pollutants and harsh weather conditions. This protective quality is crucial for maintaining the skin’s integrity and overall health.
Note: the listed benefits above are exclusively based on the officially recognized and defined functions of the ingredient, as documented by the International Nomenclature of Cosmetic Ingredients (INCI).
Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3 is generally considered safe for topical application, with a low allergenic potential. However, as with any cosmetic ingredient, there are potential side effects that users should be aware of:
Regarding individuals who are pregnant or breastfeeding, data and research on the topical usage of Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3 during pregnancy is lacking. Therefore, it is advisable for these individuals to consult a healthcare professional for further advice before using products containing this ingredient.
Side effects and adverse reactions from this ingredient are uncommon, but it is always recommended to perform a patch test before widespread usage to ensure there are no adverse reactions.
In terms of comedogenicity, Octapeptide-12 Sh-Polypeptide-56 Tripeptide-44 Sh-Polypeptide-3 has a rating of 0, meaning it is considered non-comedogenic. This makes it suitable for individuals prone to acne, blemishes, or breakouts, as it is unlikely to clog pores or exacerbate these conditions.
